Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.62 |
| ▸ | F3 | P13726 | 2/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28058155 | 0.85 | CA12 (0.63) | GSK3BF3BACE1 | |
| SCHEMBL28160312 | 0.83 | GLA (0.53) | F3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL18338902 | 0.83 | F3 (0.66) | GSK3BF3HDAC3HDAC1HDAC2 | |
| SCHEMBL6578188 | 0.83 | F3 (0.66) | GSK3BF3HDAC3HDAC1HDAC2 | |
| SCHEMBL11549072 | 0.81 | GSK3B (0.87) | GSK3BF3HDAC3HDAC1HDAC2 | |
| SCHEMBL11549066 | 0.81 | GSK3B (0.87) | GSK3BF3HDAC3HDAC1HDAC2 | |
| SCHEMBL1514193 | 0.81 | GSK3B (0.65) | GSK3BF3HDAC3HDAC1HDAC2 | |
| SCHEMBL29170010 | 0.81 | GSK3B (0.65) | GSK3BF3HDAC3HDAC1HDAC2 | |
| SCHEMBL30472929 | 0.81 | LMNA (0.63) | GSK3BF3HDAC3HDAC1HDAC2 | |
| SCHEMBL1237222 | 0.81 | GSK3B (0.73) | GSK3BF3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106795327-B | Resin composition and optical compensation film using the same | 东曹株式会社 | 2019-08-30 | — | — | CN | disclosed |
| CN-105997967-B | Compound and composition for treating cancer | 普罗米蒂克医药SMT有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-106191142-B | A kind of preparation method of the biodiesel rich in phenolic acid structure ester | 中国农业科学院油料作物研究所 | 2018-08-14 | — | — | CN | disclosed |
| CN-102883602-B | Method for reducing virulence of bacteria | UWM研究基金会有限公司 | 2017-07-18 | — | — | CN | disclosed |
| CN-106795327-A | Resin composition and optical compensation film using the same | 东曹株式会社 | 2017-05-31 | — | — | CN | disclosed |
| CN-106191142-A | A kind of preparation method of the biodiesel rich in phenolic acid structure ester | 中国农业科学院油料作物研究所 | 2016-12-07 | — | — | CN | disclosed |
| CN-105997967-A | Compounds and compositions for the treatment of cancer | 普罗米蒂克医药SMT有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105709169-A | Ointment for treating wind-damp pain of neck, shoulders, waist and legs | 徐利华 | 2016-06-29 | — | — | CN | disclosed |
| CN-103347509-B | Compounds and compositions for the treatment of cancer | 普罗米蒂克生物科学公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-105007894-A | Plant lipid composition for modulating functions of keratinous materials, method for modulating said functions and use of said plant lipids | NATURA COSMETICOS SA | 2015-10-28 | — | — | CN | disclosed |
| CN-104906345-A | Traditional Chinese medicine composition used for treating chronic obstructive pulmonary disease in stable phase | UNIV HUANGHUAI | 2015-09-16 | — | — | CN | disclosed |