SCHEMBL28030919

SCHEMBL28030919

C1=C(OC2=CCCCCC2)CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.34
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10876868 1.00 KDM1A (0.34) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL10876875 1.00 KDM1A (0.34) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL10876862 1.00 KDM1A (0.34) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL1134992 0.97 KDM1A (0.36) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL477769 0.88 HDAC3 (0.32) HDAC4HDAC2HDAC8HDAC6
SCHEMBL13721172 0.87 KDM1A (0.31) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL28422594 0.86 KDM1A (0.33) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL9702707 0.83 ALDH1A1 (0.36)
Ethylene SCHEMBL11164027 0.82 HDAC3 (0.30) HDAC4HDAC2HDAC8HDAC6
SCHEMBL8414433 0.82 KDM1A (0.34) KDM1AHDAC4HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111200933-A Active ingredient compositions comprising N-enoyl-N-alkylglucamides and their use 科莱恩国际有限公司 2020-05-26 CN disclosed
CN-107530591-A Silicone defoamer composition 瓦克化学股份公司 2018-01-02 CN disclosed
CN-107027311-A Addition-crosslinking silicone compositions having high water absorption capacity 瓦克化学股份公司 2017-08-08 CN disclosed
CN-104508032-B There is the polysiloxane composition of the addition-crosslinkable of low compression deformation 瓦克化学股份公司 2016-11-16 CN disclosed
CN-103403067-B Amphipathic high index of refraction organopolysiloxane 瓦克化学股份公司 2016-09-14 CN disclosed
CN-105899618-A Surfactant-free organopolysiloxane invert emulsions 瓦克化学股份公司 2016-08-24 CN disclosed
CN-105026023-A Asymmetric porous membranes made from crosslinked thermoplastic silicone elastomers WACKER CHEMIE AG 2015-11-04 CN disclosed