SCHEMBL28031074

SCHEMBL28031074

NC(=O)c1cccc(C(=O)Nc2ccc(NC(=O)c3ccccc3)cc2)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 0.69
KMT2A Q03164 4/20 0.67
MEN1 O00255 3/20 0.67
HDAC1 Q13547 1/20 0.65
HDAC2 Q92769 1/20 0.65
HDAC8 Q9BY41 1/20 0.65
HDAC6 Q9UBN7 1/20 0.65
PTPN1 P18031 2/20 0.62
KCNK3 O14649 1/20 0.62
KCNK9 Q9NPC2 1/20 0.62
TP53 P04637 1/20 0.62
NPC1 O15118 3/20 0.61
RAB9A P51151 3/20 0.61
POLB P06746 2/20 0.61
SIRT1 Q96EB6 2/20 0.61
KDM4E B2RXH2 1/20 0.61
SIRT2 Q8IXJ6 2/20 0.59
PKM P14618 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
MAPT P10636 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3069463 0.95 PLAU (0.76) PLAUKMT2AMEN1HDAC1HDAC2
SCHEMBL28031075 0.92 KCNK3 (0.77) PLAUKMT2AMEN1HDAC1HDAC2
SCHEMBL14715851 0.91 KMT2A (0.79) KMT2AMEN1HDAC1HDAC2HDAC8
SCHEMBL28595821 0.90 KMT2A (0.84) PLAUKMT2AMEN1HDAC1HDAC2
SCHEMBL9746979 0.88 PTGS1 (0.64) PLAUKMT2AMEN1HDAC1HDAC2
SCHEMBL4004339 0.88 KCNK3 (0.76) PLAUKMT2AMEN1KCNK3KCNK9
SCHEMBL3902965 0.87 KMT2A (0.72) PLAUKMT2AMEN1PTPN1NPC1
SCHEMBL7244321 0.87 PLAU (0.61) PLAUKMT2AMEN1HDAC1HDAC2
SCHEMBL7242720 0.87 TP53 (0.84) PLAUKMT2AMEN1HDAC1HDAC2
SCHEMBL7234929 0.87 MEN1 (0.58) PLAUKMT2AMEN1HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103764793-B High flow liquid crystalline polymer composition 提克纳有限责任公司 2016-09-14 CN disclosed
CN-103764623-B Aromatic amide compounds TICONA LLC (US) 2016-04-27 CN disclosed
CN-103764741-B The melt polymerization of low melt viscosity liquid crystalline polymers TICONA LLC (US) 2015-09-23 CN disclosed