SCHEMBL28031372

SCHEMBL28031372

CCCCc1cc(CCCC)c(O)c(CCCC)c1.[NaH]

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.55
HPGD P15428 1/20 0.55
MAPK1 P28482 1/20 0.55
HTT P42858 1/20 0.55
RAB9A P51151 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
PTGS2 P35354 7/20 0.52
CYP3A4 P08684 1/20 0.52
TYR P14679 1/20 0.47
ALOX5 P09917 4/20 0.44
EGFR P00533 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL201692 0.98 NPC1 (0.57) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL27977349 0.96 NPC1 (0.55) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL28215541 0.96 NPC1 (0.55) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL1022838 0.94 NPC1 (0.53) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL11801101 0.94 PTGS2 (0.61) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL5171088 0.92 NPC1 (0.52) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL1023152 0.92 HPGD (0.52) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL11773665 0.92 PTGS2 (0.62) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL201072 0.92 PTGS2 (0.62) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL13124313 0.92 PTGS2 (0.62) NPC1HPGDMAPK1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106458823-A Process for preparing unsaturated carboxylic acid salts 巴斯夫欧洲公司 2017-02-22 CN claimed
CN-105008378-B The manufacturing method of cross-coupling catalysts and aromatic compound 北兴化学工业株式会社 2018-05-18 CN disclosed
CN-105008378-A Reaction catalyst for cross coupling and method for manufacturing aromatic compound HOKKO CHEM IND CO 2015-10-28 CN disclosed