Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031582 | 0.90 | HTR1D (0.38) | HTR1DHTR1BGABRA1GABRB2SLC22A6 | |
| SCHEMBL27584061 | 0.84 | HTR1D (0.46) | HTR1DHTR1BGABRA1GABRB2SLC22A6 | |
| SCHEMBL27596759 | 0.81 | HTR1D (0.46) | HTR1DHTR1BGABRA1GABRB2SLC22A6 | |
| SCHEMBL27623627 | 0.81 | L3MBTL1 (0.45) | HTR1DHTR1BSLC22A6 | |
| SCHEMBL27623616 | 0.77 | NR4A2 (0.40) | HTR1DHTR1BSLC22A6 | |
| SCHEMBL27667193 | 0.77 | HTR1D (0.50) | HTR1DHTR1BSLC22A6ELANE | |
| SCHEMBL27751359 | 0.77 | NR4A2 (0.52) | HTR1DHTR1BGABRA1GABRB2SLC22A6 | |
| SCHEMBL27591862 | 0.77 | NR4A2 (0.52) | HTR1DHTR1BGABRA1GABRB2SLC22A6 | |
| SCHEMBL28000737 | 0.77 | HTR1D (0.45) | HTR1DHTR1BSLC22A6ELANE | |
| SCHEMBL27752468 | 0.77 | HTR1D (0.45) | HTR1DHTR1BGABRA1SLC22A6ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104854088-A | Novel indole derivatives for the treatment of cancer, viral infections and lung diseases | BIOKINESIS | 2015-08-19 | — | — | CN | disclosed |