Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29378766 | 0.88 | KMT2A (0.55) | DAOCA12BRD4BRPF1CA9 | |
| SCHEMBL154592 | 0.88 | KMT2A (0.55) | DAOCA12BRD4BRPF1CA9 | |
| Ammonia Solution, Strong SCHEMBL28142197 | 0.86 | KMT2A (0.53) | DAOCA12BRD4BRPF1CA9 | |
| Cyanide SCHEMBL6526282 | 0.82 | KMT2A (0.50) | DAOCA12BRD4BRPF1CA9 | |
| SCHEMBL27898683 | 0.81 | DAO (0.47) | DAOCA12BRD4BRPF1CA9 | |
| Formamide SCHEMBL8533326 | 0.81 | DAO (0.47) | DAOCA12BRD4BRPF1CA9 | |
| SCHEMBL5700702 | 0.81 | KMT2A (0.53) | DAOCA12BRD4BRPF1CA9 | |
| SCHEMBL1172151 | 0.81 | KMT2A (0.53) | DAOCA12BRD4BRPF1CA9 | |
| SCHEMBL29528615 | 0.81 | KMT2A (0.53) | DAOCA12BRD4BRPF1CA9 | |
| Formamide SCHEMBL29013060 | 0.80 | DAO (0.46) | DAOCA12BRD4BRPF1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341799-B | Novel indole derivatives for the treatment of cancer, viral infections and lung diseases | 生物控制术公司 | 2022-01-25 | — | — | CN | disclosed |
| CN-104854088-A | Novel indole derivatives for the treatment of cancer, viral infections and lung diseases | BIOKINESIS | 2015-08-19 | — | — | CN | disclosed |