Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27173414 | 0.82 | CYP3A4 (0.39) | EPHX1CYP1A2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL27173344 | 0.80 | CHRM2 (0.41) | — | |
| SCHEMBL14402570 | 0.79 | PNMT (0.64) | EPHX1PNMTTAS1R3TAS1R1HDAC3 | |
| SCHEMBL1213326 | 0.79 | EPHX1 (0.49) | EPHX1PNMTTAS1R3TAS1R1HDAC3 | |
| SCHEMBL20342674 | 0.79 | PNMT (0.64) | EPHX1PNMTTAS1R3TAS1R1HDAC3 | |
| SCHEMBL27511992 | 0.79 | PNMT (0.47) | EPHX1PNMTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1730600 | 0.78 | EPHX1 (0.51) | EPHX1PNMTTAS1R3TAS1R1HDAC3 | |
| SCHEMBL21124992 | 0.78 | EPHX1 (0.48) | EPHX1PNMTTAS1R3TAS1R1HDAC3 | |
| SCHEMBL18885350 | 0.78 | EPHX1 (0.48) | EPHX1PNMTTAS1R3TAS1R1HDAC3 | |
| SCHEMBL7384477 | 0.78 | EPHX1 (0.48) | EPHX1PNMTTAS1R3TAS1R1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104918942-A | Pyrimidone derivatives and their use for treating, ameliorating or preventing viral diseases | SAVIRA PHARMACEUTICALS GMBH | 2015-09-16 | — | — | CN | disclosed |