Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | PLEC | Q15149 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031622 | 0.91 | KMT2A (0.43) | HTTMEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL28032234 | 0.89 | MEN1 (0.45) | HTTMEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL28078513 | 0.89 | MEN1 (0.49) | HTTMEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL28031651 | 0.87 | KMT2A (0.48) | HTTMEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL28031775 | 0.84 | TP53 (0.45) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL28032227 | 0.84 | HTT (0.41) | HTTMEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL28031624 | 0.84 | GAA (0.46) | HTTMEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL28031631 | 0.84 | PTPN11 (0.47) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL28032237 | 0.83 | HTT (0.40) | HTTMEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL28031656 | 0.82 | HTT (0.43) | HTTMEN1KMT2AGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646322-A | Perfluoroalkyl pyrrole derivative and synthesis method thereof | 上海大学 | 2016-06-08 | — | — | CN | disclosed |
| CN-105017126-A | Perfluoroalkyl pyrrole derivative and synthesis method thereof | UNIV SHANGHAI | 2015-11-04 | — | — | CN | disclosed |