Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 11/20 | 0.51 |
| ▸ | PARP1 | P09874 | 8/20 | 0.51 |
| ▸ | PARP11 | Q9NR21 | 8/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31160537 | 0.82 | CLK4 (0.44) | PARP10PARP1PARP11F7F3 | |
| SCHEMBL18304941 | 0.81 | PARP10 (0.53) | PARP10PARP1PARP11CDK2ACHE | |
| SCHEMBL30362890 | 0.81 | PARP10 (0.53) | PARP10PARP1PARP11CDK2ACHE | |
| SCHEMBL32669251 | 0.79 | PARP10 (0.51) | PARP10PARP1PARP11F7F3 | |
| SCHEMBL21237626 | 0.76 | PARP10 (0.51) | PARP10PARP1PARP11F7F3 | |
| SCHEMBL24886285 | 0.76 | PARP10 (0.56) | PARP10PARP1PARP11F7F3 | |
| SCHEMBL32669326 | 0.76 | PARP10 (0.44) | PARP10PARP1PARP11F7F3 | |
| SCHEMBL11184319 | 0.76 | PARP1 (0.45) | PARP10PARP1PARP11F7F3 | |
| SCHEMBL22547426 | 0.74 | SIRT2 (0.35) | PARP10PARP1NOTUMMEN1KMT2A | |
| SCHEMBL30676593 | 0.74 | SIRT2 (0.35) | PARP10PARP1NOTUMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870435-A | Aryl and heteroaryl fused lactams | PFIZER | 2015-08-26 | — | — | CN | disclosed |