Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.51 |
| ▸ | PARP1 | P09874 | 8/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 7/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CDK16 | Q00536 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31159005 | 0.82 | GRM2 (0.46) | PARP10PARP1PIM1DYRK1ADYRK1B | |
| SCHEMBL23951998 | 0.79 | PARP10 (0.56) | PARP10PARP1PARP11PARP2DYRK3 | |
| SCHEMBL28032373 | 0.79 | PARP10 (0.51) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL30197872 | 0.79 | PARP10 (0.56) | PARP10PARP1PARP11PARP2DYRK3 | |
| SCHEMBL32669434 | 0.78 | PARP1 (0.50) | PARP10PARP1PARP11PARP2DYRK3 | |
| SCHEMBL32669326 | 0.76 | PARP10 (0.44) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL32669380 | 0.76 | PARP1 (0.47) | PARP10PARP1PARP11PARP2DYRK3 | |
| SCHEMBL11184319 | 0.76 | PARP1 (0.45) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL24681002 | 0.75 | PARP10 (0.42) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL1405476 | 0.74 | NOTUM (0.50) | PARP10PARP1NOTUMCDK2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260034126-A1 | KRAS INHIBITORS | INCYTE CORP (US) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034126-A1 | KRAS INHIBITORS | KRAS, NRAS, HRAS | PARP10 660/4885PARP1 2245/4885F7 4273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.