SCHEMBL28032380

SCHEMBL28032380

C=Cc1ccc(N2COc3ccccc3C2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
NPC1 O15118 5/20 0.35
RAB9A P51151 5/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 5/20 0.34
TSHR P16473 1/20 0.34
MAPT P10636 3/20 0.33
TP53 P04637 1/20 0.33
BACE1 P56817 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
OXTR P30559 1/20 0.31
VDR P11473 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
HSD17B3 P37058 1/20 0.31
PKM P14618 1/20 0.31
HTR1A P08908 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20932611 0.87 MEN1 (0.47) MEN1GAAKMT2ANPC1RAB9A
SCHEMBL12808967 0.82 MEN1 (0.43) MEN1GAAKMT2ANPC1RAB9A
SCHEMBL802947 0.82 NPC1 (0.44) MEN1GAAKMT2ANPC1RAB9A
SCHEMBL17191289 0.80 MEN1 (0.57) MEN1GAAKMT2ANPC1RAB9A
SCHEMBL19404570 0.80 VDR (0.41) MEN1GAAKMT2ANPC1RAB9A
SCHEMBL12162755 0.80 TSHR (0.47) MEN1GAAKMT2ANPC1RAB9A
SCHEMBL95039 0.78 NPC1 (0.44) MEN1GAAKMT2ANPC1RAB9A
SCHEMBL21160834 0.78 MEN1 (0.40) MEN1GAAKMT2ANPC1RAB9A
SCHEMBL13203349 0.78 MEN1 (0.40) MEN1GAAKMT2ANPC1RAB9A
SCHEMBL15358745 0.78 NPC1 (0.47) MEN1GAAKMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104926749-A Benzoxazine monomer comprising vinyl benzene structure, and application and preparation method of benzoxazine monomer UNIV HUAZHONG SCIENCE TECH 2015-09-23 CN disclosed