SCHEMBL28032452

SCHEMBL28032452

NC1(F)C=CC=CC1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9434282 0.74
SCHEMBL5153426 0.72
SCHEMBL28675570 0.72
SCHEMBL27553143 0.72
SCHEMBL29137437 0.69
SCHEMBL4696091 0.69
SCHEMBL1989509 0.68
SCHEMBL283465 0.68
SCHEMBL779916 0.68
SCHEMBL17925957 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108947850-B Preparation method of 3,4, 5-trifluoroaniline 蚌埠中实化学技术有限公司 2021-05-18 CN disclosed
CN-108947850-A A kind of preparation method of 3,4,5- trifluoromethyl aniline 蚌埠中实化学技术有限公司 2018-12-07 CN disclosed
CN-104844412-B A kind of preparation method of 1,2,4-trifluoro-benzene 浙江林江化工股份有限公司 2016-06-08 CN disclosed
CN-104844412-A Preparation method of 1,2,4-trifluorobenzene ZHEJIANG LINJIANG CHEMICAL CO LTD 2015-08-19 CN disclosed