Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 6/20 | 0.57 |
| ▸ | HTR1A | P08908 | 5/20 | 0.57 |
| ▸ | HTR7 | P34969 | 5/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.54 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | DRD3 | P35462 | 4/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31173766 | 0.98 | ALOX15 (0.60) | ALOX15HTTSMN1; SMN2DRD2HTR1A | |
| SCHEMBL175532 | 0.98 | ALOX15 (0.60) | ALOX15HTTSMN1; SMN2DRD2HTR1A | |
| SCHEMBL30093449 | 0.97 | ALOX15 (0.59) | ALOX15HTTSMN1; SMN2DRD2HTR1A | |
| SCHEMBL9155744 | 0.97 | ALOX15 (0.59) | ALOX15HTTSMN1; SMN2DRD2HTR1A | |
| SCHEMBL29858270 | 0.97 | ALOX15 (0.59) | ALOX15HTTSMN1; SMN2DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL3192243 | 0.97 | ALOX15 (0.59) | ALOX15HTTSMN1; SMN2DRD2HTR1A | |
| SCHEMBL11596488 | 0.97 | ALOX15 (0.59) | ALOX15HTTSMN1; SMN2DRD2HTR1A | |
| SCHEMBL27899642 | 0.97 | ALOX15 (0.59) | ALOX15HTTSMN1; SMN2DRD2HTR1A | |
| SCHEMBL27899648 | 0.97 | ALOX15 (0.59) | ALOX15HTTSMN1; SMN2DRD2HTR1A | |
| SCHEMBL10650175 | 0.97 | ALOX15 (0.59) | ALOX15HTTSMN1; SMN2DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272936-B | A kind of nitrogen aryl benzothiazoles PARP inhibitor and its preparation method and application | 中国科学院上海药物研究所 | 2019-05-17 | — | — | CN | disclosed |
| CN-105272936-B | A kind of nitrogen aryl benzothiazoles PARP inhibitor and its preparation method and application | 中国科学院上海药物研究所 | 2019-05-17 | — | — | CN | disclosed |
| CN-105272936-B | A kind of nitrogen aryl benzothiazoles PARP inhibitor and its preparation method and application | 中国科学院上海药物研究所 | 2019-05-17 | — | — | CN | disclosed |
| CN-105272936-A | Nitrogen aryl benzothiazole PARP inhibitors, preparation methods and uses thereof | SHANGHAI INST MATERIA MEDICA | 2016-01-27 | — | — | CN | disclosed |
| CN-105272936-A | Nitrogen aryl benzothiazole PARP inhibitors, preparation methods and uses thereof | SHANGHAI INST MATERIA MEDICA | 2016-01-27 | — | — | CN | disclosed |
| CN-105272936-A | Nitrogen aryl benzothiazole PARP inhibitors, preparation methods and uses thereof | SHANGHAI INST MATERIA MEDICA | 2016-01-27 | — | — | CN | disclosed |