Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 16/20 | 0.70 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.70 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.52 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.52 |
| ▸ | NPY4R | P50391 | 8/20 | 0.51 |
| ▸ | NPY2R | P49146 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1593464 | 1.00 | NPY1R (0.70) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL8127508 | 0.85 | NPY4R (0.64) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL3817640 | 0.85 | NPY1R (0.51) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL650331 | 0.84 | NPY1R (0.72) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL8587072 | 0.84 | NPY1R (0.52) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL9982932 | 0.84 | NPY1R (0.53) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| Hydrochloric Acid SCHEMBL27545598 | 0.84 | NPY1R (0.50) | NPY1RNPY5RNPY4RNPY2R | |
| SCHEMBL28882485 | 0.82 | NPY1R (1.00) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL1388524 | 0.82 | NPY1R (0.49) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL5317095 | 0.82 | NPY1R (0.49) | NPY1RNPY5RNPFFR1NPFFR2NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024352-A | Novel inhibitors | 维沃里翁治疗股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-108218849-B | Novel inhibitors | 维沃永治疗公众有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-111315738-B | Inhibitors of glutaminyl cyclase | 维沃永治疗股份公司 | 2021-08-03 | — | — | CN | disclosed |
| CN-110719910-A | Novel inhibitors | 前体生物药物股份公司 | 2020-01-21 | — | — | CN | disclosed |
| CN-105263927-B | Inhibitors of glutaminyl cyclase | 前体生物药物股份公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-108218849-A | New inhibitor | 前体生物药物股份公司 | 2018-06-29 | — | — | CN | disclosed |
| CN-102186475-B | novel inhibitors | 前体生物药物股份公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-105263927-A | Novel inhibitors | PROBILDRUG AG | 2016-01-20 | — | — | CN | disclosed |
| CN-102791704-B | The heterocycle inhibitor of glutaminyl cyclase (QC, EC 2.3.2.5) | PROBIODRUG AG (DE) | 2015-11-25 | — | — | CN | disclosed |