Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.38 |
| ▸ | DRD4 | P21917 | 5/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28269313 | 0.79 | NPC1 (0.38) | HCAR2MAPTSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL28032854 | 0.73 | HCAR2 (0.40) | HCAR2HCAR3MKNK1MKNK2DRD4 | |
| SCHEMBL28033351 | 0.72 | HCAR2 (0.41) | HCAR2HCAR3MKNK1MKNK2DRD4 | |
| SCHEMBL27983075 | 0.66 | HCAR2 (0.50) | HCAR2HCAR3MKNK1MKNK2DRD4 | |
| SCHEMBL56939 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL17107724 | 0.63 | HCAR2 (0.48) | HCAR2HCAR3MKNK1MKNK2CCNA2 | |
| SCHEMBL30558789 | 0.63 | MKNK1 (0.54) | HCAR2HCAR3MKNK1MKNK2LMNA | |
| SCHEMBL27977175 | 0.63 | MKNK1 (0.54) | HCAR2HCAR3MKNK1MKNK2LMNA | |
| SCHEMBL4457723 | 0.60 | HCAR2 (0.43) | HCAR2HCAR3MKNK1MKNK2LMNA | |
| SCHEMBL4455888 | 0.60 | HCAR2 (0.43) | HCAR2HCAR3MKNK1MKNK2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377261-A | Substituted indol-5-ol derivatives and their therapeutic use | NANTBIO INC | 2016-03-02 | — | — | CN | disclosed |
| CN-104955459-A | Substituted indol-5-ol derivatives and their therapeutical applications | NANT HOLDINGS IP LLC | 2015-09-30 | — | — | CN | disclosed |