Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28032853 | 0.79 | HCAR2 (0.39) | HCAR2SMN1; SMN2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28269314 | 0.72 | NPC1 (0.41) | NPC1KDM4EGAAHSD17B10L3MBTL1 | |
| SCHEMBL28411462 | 0.64 | MAPT (0.44) | NPC1KDM4EGAAHSD17B10L3MBTL1 | |
| SCHEMBL29565779 | 0.64 | MAPT (0.44) | NPC1KDM4EGAAHSD17B10L3MBTL1 | |
| Hydrochloric Acid SCHEMBL29565430 | 0.63 | MAPT (0.43) | NPC1KDM4EGAAHSD17B10L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28411373 | 0.63 | MAPT (0.43) | NPC1KDM4EGAAHSD17B10L3MBTL1 | |
| SCHEMBL27579167 | 0.63 | HTT (0.47) | NPC1KDM4EGAAHSD17B10RAB9A | |
| SCHEMBL4169628 | 0.61 | NPC1 (0.49) | NPC1KDM4EGAAHSD17B10L3MBTL1 | |
| SCHEMBL3946606 | 0.61 | HCAR2 (0.52) | NPC1KDM4EGAAHSD17B10L3MBTL1 | |
| SCHEMBL18027880 | 0.60 | L3MBTL1 (0.59) | NPC1KDM4EGAAHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104955459-B | Substituted indoles -5- amphyl and its treatment use | 南特知识产权控股有限责任公司 | 2019-02-01 | — | — | CN | disclosed |