SCHEMBL28032876

SCHEMBL28032876

CC(C)OC(=O)C(Cc1ccc(N)cc1)NC(=O)c1c(Cl)cccc1Cl

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ITGB1 P05556 19/20 0.53
ITGA4 P13612 16/20 0.53
ITGB7 P26010 3/20 0.53
ITGA2 P17301 1/20 0.53
ITGA5 P08648 3/20 0.48
PSMB5 P28074 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL370312 1.00 ITGB1 (0.53) ITGB1ITGA4ITGB7ITGA2ITGA5
SCHEMBL18067798 0.89 ITGB1 (0.56) ITGB1ITGA4ITGB7ITGA2ITGA5
SCHEMBL298056 0.89 PSMB5 (0.59) ITGB1ITGA4ITGB7ITGA2ITGA5
SCHEMBL1240417 0.89 ITGB1 (0.53) ITGB1ITGA4ITGB7ITGA2ITGA5
SCHEMBL295783 0.89 ITGB1 (0.53) ITGB1ITGA4ITGB7ITGA2ITGA5
SCHEMBL371384 0.88 LNPEP (0.44) ITGB1ITGA4ITGB7ITGA2
Hydrochloric Acid SCHEMBL7391192 0.88 ITGB1 (0.52) ITGB1ITGA4ITGB7ITGA2ITGA5
SCHEMBL12123726 0.87 ITGB1 (0.55) ITGB1ITGA4ITGB7ITGA2ITGA5
SCHEMBL299984 0.84 ITGB1 (0.50) ITGB1ITGA4ITGB7ITGA2ITGA5
SCHEMBL12123728 0.84 ITGB1 (0.50) ITGB1ITGA4ITGB7ITGA2ITGA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103784458-B Phenylalamine derivatives AJINOMOTO K. K. (JP) 2015-10-14 CN disclosed