Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.62 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21802163 | 1.00 | SPHK2 (0.62) | SPHK2SPHK1ALDH1A1LMNAPOLB | |
| SCHEMBL20298428 | 0.98 | SPHK2 (0.59) | SPHK2SPHK1ALDH1A1LMNAPOLB | |
| SCHEMBL27585249 | 0.98 | SPHK2 (0.59) | SPHK2SPHK1ALDH1A1LMNAPOLB | |
| SCHEMBL31038604 | 0.93 | SPHK2 (0.50) | SPHK2SPHK1ALDH1A1LMNAPOLB | |
| SCHEMBL27689668 | 0.84 | SOAT1 (0.48) | ALDH1A1ALOX15KDM4EMEN1KMT2A | |
| Octane SCHEMBL1843443 | 0.83 | LMNA (0.50) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| Dodecane SCHEMBL28288842 | 0.83 | LMNA (0.50) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| Decane SCHEMBL27812031 | 0.83 | LMNA (0.50) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| Hexane SCHEMBL27317543 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL31289294 | 0.79 | LMNA (0.42) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104968340-A | USES AND METHODS FOR THE TREATMENT OF LIVER DISEASES OR CONDITIONS | ONCOZYME PHARMA INC | 2015-10-07 | — | — | CN | disclosed |