Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 14/20 | 0.61 |
| ▸ | EP300 | Q09472 | 5/20 | 0.55 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28032559 | 1.00 | HSD11B1 (0.61) | HSD11B1EP300CREBBPALDH1A1 | |
| SCHEMBL28032575 | 0.96 | HSD11B1 (0.57) | HSD11B1EP300CREBBP | |
| SCHEMBL349841 | 0.78 | HSD11B1 (0.62) | HSD11B1EP300CREBBPALDH1A1 | |
| SCHEMBL350755 | 0.78 | HSD11B1 (0.62) | HSD11B1EP300CREBBPALDH1A1 | |
| SCHEMBL350015 | 0.78 | HSD11B1 (0.62) | HSD11B1EP300CREBBPALDH1A1 | |
| SCHEMBL348537 | 0.76 | HSD11B1 (0.60) | HSD11B1EP300CREBBPALDH1A1 | |
| SCHEMBL348064 | 0.76 | HSD11B1 (1.00) | HSD11B1ALDH1A1 | |
| SCHEMBL27694837 | 0.76 | HSD11B1 (0.58) | HSD11B1 | |
| SCHEMBL5744053 | 0.75 | HSD11B1 (0.62) | HSD11B1EP300CREBBPALDH1A1 | |
| SCHEMBL5744055 | 0.75 | HSD11B1 (0.62) | HSD11B1EP300CREBBPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101001842-B | Amido compounds and the application as medicine thereof | INCYTE CORP. (US) | 2015-10-07 | — | — | CN | disclosed |