Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329737 | 0.98 | TP53 (0.56) | TP53DPP7SLC15A1FDPSRECQL | |
| Hydrochloric Acid SCHEMBL28075551 | 0.95 | TP53 (0.54) | TP53DPP7SLC15A1FDPSRECQL | |
| SCHEMBL8677764 | 0.93 | TP53 (0.63) | TP53FDPSOPRM1CA1SPHK1 | |
| SCHEMBL8585540 | 0.91 | TP53 (0.61) | TP53FDPSOPRM1CA1SPHK1 | |
| SCHEMBL27699386 | 0.91 | TP53 (0.61) | TP53FDPSOPRM1CA1SPHK1 | |
| SCHEMBL27719831 | 0.91 | TP53 (0.61) | TP53FDPSOPRM1CA1SPHK1 | |
| SCHEMBL3924986 | 0.91 | TP53 (0.61) | TP53FDPSOPRM1CA1SPHK1 | |
| SCHEMBL9661281 | 0.91 | TP53 (0.61) | TP53FDPSOPRM1CA1SPHK1 | |
| SCHEMBL692235 | 0.91 | TP53 (0.65) | TP53FDPSOPRM1CA1SPHK1 | |
| SCHEMBL10891420 | 0.88 | TP53 (0.63) | TP53FDPSOPRM1CA1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611001-B | Utilize the method for hydrosulphite Intermediate Preparation 6,6-dimethyl-3-azabicyclo-[3.1.0]-hexane compound | MERCK SHARP & DOHME CORP. (US) | 2015-11-25 | — | — | CN | claimed |
| CN-101611001-B | Utilize the method for hydrosulphite Intermediate Preparation 6,6-dimethyl-3-azabicyclo-[3.1.0]-hexane compound | MERCK SHARP & DOHME CORP. (US) | 2015-11-25 | — | — | CN | disclosed |