Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.47 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | EYA2 | O00167 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033532 | 1.00 | FOLH1 (0.47) | FOLH1NAALAD2RIMKLATDP1EYA2 | |
| SCHEMBL30670301 | 0.88 | FOLH1 (0.40) | FOLH1NAALAD2RIMKLATDP1EYA2 | |
| SCHEMBL7882789 | 0.82 | FOLH1 (0.38) | FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL27092866 | 0.82 | TDP1 (0.46) | TDP1EYA2APPACEBLM | |
| SCHEMBL27092877 | 0.82 | TDP1 (0.46) | TDP1EYA2APPACEBLM | |
| SCHEMBL29223077 | 0.81 | TDP1 (0.41) | FOLH1NAALAD2RIMKLATDP1EYA2 | |
| SCHEMBL29223072 | 0.81 | TDP1 (0.41) | FOLH1NAALAD2RIMKLATDP1EYA2 | |
| SCHEMBL27404937 | 0.81 | FOLH1 (0.34) | FOLH1NAALAD2RIMKLATDP1EYA2 | |
| SCHEMBL3905513 | 0.81 | NOD1 (0.44) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL8768068 | 0.81 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLAGGHGGT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108289970-B | Formulations comprising a combination of MRI contrast agents | 通用电气医疗集团股份有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-112807449-A | Magnetic resonance imaging contrast agent comprising T1 contrast material coated on the surface of a nanoparticle carrier | 茵温特拉制药公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112089851-A | Magnetic resonance imaging contrast agent comprising T1 contrast material coated on the surface of a nanoparticle carrier | 茵温特拉制药公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-104955486-A | Magnetic resonance imaging contrast agent comprising T1 contrast material coated on the surface of a nanoparticle carrier | UNIV YONSEI IACF | 2015-09-30 | — | — | CN | disclosed |