SCHEMBL28033746

SCHEMBL28033746

C=CC(=O)OCCCCOC(=O)C(C)=CCCO

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.55
ALDH1A1 P00352 4/20 0.55
CYP3A4 P08684 2/20 0.55
HPGD P15428 1/20 0.50
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
HSD17B10 Q99714 1/20 0.42
THRB P10828 2/20 0.36
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ATM Q13315 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
HCAR2 Q8TDS4 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4606584 0.94 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5025149 0.89 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL10879518 0.86 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL27569910 0.84 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL21612157 0.83 TSHR (0.35) TSHRALDH1A1ATMCYP2D6CYP2C19
SCHEMBL11029241 0.83 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL27940506 0.83 TSHR (0.67) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL6368769 0.83 TSHR (0.56) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL14718061 0.82 TSHR (0.51) TSHRALDH1A1ATMHCAR2
SCHEMBL5325148 0.82 TSHR (0.64) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103464223-B A kind of process aromatic sulphonic acid waste water anion exchange resin and preparation method thereof Kai Rui environmental protection Science and Technology Co., Ltd. (CN) 2015-12-02 CN disclosed