Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29815450 | 0.82 | — | — | |
| SCHEMBL97422 | 0.82 | — | — | |
| SCHEMBL1509673 | 0.82 | TDP1 (0.63) | LMNAMEN1KMT2ATHRBBLM | |
| Methyl Alcohol SCHEMBL28778721 | 0.80 | TDP1 (0.55) | LMNAMEN1KMT2ATHRBBLM | |
| SCHEMBL29924187 | 0.80 | TDP1 (0.60) | LMNAMEN1KMT2ATHRBBLM | |
| Methane SCHEMBL10926734 | 0.80 | TDP1 (0.60) | LMNAMEN1KMT2ATHRBBLM | |
| Hydrochloric Acid SCHEMBL10816378 | 0.80 | TDP1 (0.60) | LMNAMEN1KMT2ATHRBBLM | |
| SCHEMBL29684596 | 0.80 | TDP1 (0.60) | LMNAMEN1KMT2ATHRBBLM | |
| Phosphine SCHEMBL27593892 | 0.80 | TDP1 (0.60) | LMNAMEN1KMT2ATHRBBLM | |
| Salicyladehyde SCHEMBL15016 | 0.79 | TRIM24 (0.69) | PTGDR2LMNAMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104861927-A | Environment-friendly ceramic brake pad | QINGDAO BAIQIANCHUAN MARINE ECOLOGICAL TECHNOLOGY CO LTD | 2015-08-26 | — | — | CN | claimed |
| CN-104058734-A | Easily-machined ceramic | XIE WEIJIE | 2014-09-24 | — | — | CN | claimed |
| CN-108123373-A | A kind of fire resisting electrical cabinet | 国网河南省电力公司安阳供电公司 | 2018-06-05 | — | — | CN | disclosed |
| CN-104861927-A | Environment-friendly ceramic brake pad | QINGDAO BAIQIANCHUAN MARINE ECOLOGICAL TECHNOLOGY CO LTD | 2015-08-26 | — | — | CN | disclosed |
| CN-104861927-A | Environment-friendly ceramic brake pad | QINGDAO BAIQIANCHUAN MARINE ECOLOGICAL TECHNOLOGY CO LTD | 2015-08-26 | — | — | CN | disclosed |
| CN-104058734-A | Easily-machined ceramic | XIE WEIJIE | 2014-09-24 | — | — | CN | disclosed |
| CN-104058734-A | Easily-machined ceramic | XIE WEIJIE | 2014-09-24 | — | — | CN | disclosed |