Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL27325031 | 0.88 | ALDH1A1 (0.64) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| Styrene SCHEMBL27829265 | 0.88 | ALDH1A1 (0.64) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| Styrene SCHEMBL27756866 | 0.86 | ALDH1A1 (0.61) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| Styrene SCHEMBL3805025 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| Styrene SCHEMBL27316735 | 0.82 | ALDH1A1 (0.78) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| Styrene SCHEMBL28064670 | 0.82 | ALDH1A1 (0.78) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| Styrene SCHEMBL15656 | 0.82 | ALDH1A1 (0.78) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| Styrene SCHEMBL7904441 | 0.82 | ALDH1A1 (0.78) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| Styrene SCHEMBL10892600 | 0.82 | ALDH1A1 (1.00) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| Styrene SCHEMBL9776790 | 0.82 | ALDH1A1 (1.00) | ALDH1A1TSHRHDAC8TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102971333-B | Process for preparing DOPO-derived compounds and compositions thereof | ALBEMARLE CORP. (US) | 2015-09-09 | — | — | CN | claimed |
| CN-105153233-A | Process for preparation of DOPO-derived compounds and compositions thereof | ALBEMARLE CORP | 2015-12-16 | — | — | CN | disclosed |
| CN-102971333-B | Process for preparing DOPO-derived compounds and compositions thereof | ALBEMARLE CORP. (US) | 2015-09-09 | — | — | CN | disclosed |