Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12897966 | 0.78 | MAPT (0.57) | L3MBTL1ALDH1A1TDP1MAPTLMNA | |
| SCHEMBL27606887 | 0.76 | BCL9 (0.72) | BCL9CTNNB1ALDH1A1TDP1MAPT | |
| SCHEMBL1632528 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNAHPGDAKR1C3 | |
| SCHEMBL27606934 | 0.75 | BCL9 (0.54) | BCL9CTNNB1ALDH1A1MAPTLMNA | |
| SCHEMBL2325339 | 0.74 | MAPT (0.53) | ALDH1A1TDP1MAPTLMNAHPGD | |
| SCHEMBL4076672 | 0.73 | ALDH1A1 (0.46) | BCL9CTNNB1ALDH1A1TDP1MAPT | |
| SCHEMBL260287 | 0.72 | AKR1C3 (0.41) | ALDH1A1MAPTLMNAHPGDAKR1C3 | |
| SCHEMBL28772952 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAHPGDKMT2A | |
| SCHEMBL28446845 | 0.70 | BCL9 (0.62) | BCL9CTNNB1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL22065493 | 0.70 | AKR1C3 (0.39) | ALDH1A1TDP1MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102264697-B | Biosynthetically generated pyrroline-carboxy-lysine and site-specific protein modification by chemical derivatization of pyrroline-carboxy-lysine and pyrrolysine residues | IRM LLC (BM) | 2015-09-09 | — | — | CN | disclosed |