SCHEMBL28034034

SCHEMBL28034034

Fc1c(Cl)cccc1OCC(F)F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.46
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
USP2 O75604 1/20 0.37
HTT P42858 1/20 0.37
CACNA1G O43497 2/20 0.36
CASR P41180 1/20 0.35
CYP1A2 P05177 1/20 0.35
GAA P10253 1/20 0.35
CYP2C19 P33261 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HTR2A P28223 2/20 0.35
HTR2C P28335 2/20 0.35
HTR2B P41595 2/20 0.35
HTR1D P28221 2/20 0.35
CFD P00746 1/20 0.34
RAB9A P51151 1/20 0.34
GCK P35557 1/20 0.34
TSHR P16473 1/20 0.33
HCRTR1 O43613 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28782681 0.81 SLC6A2 (0.44) KMT2ATDP1
SCHEMBL767885 0.78 NR2E1 (0.55) MRGPRX4MEN1KMT2AUSP2HTT
SCHEMBL767886 0.78 NR2E1 (0.55) MRGPRX4MEN1KMT2AUSP2HTT
SCHEMBL15153657 0.77 MRGPRX4 (0.48) MRGPRX4MEN1KMT2ACACNA1GCYP1A2
SCHEMBL2883927 0.77 L3MBTL1 (0.51) MRGPRX4CYP1A2GAACYP2C19TDP1
SCHEMBL30958477 0.76 KMT2A (0.47) KMT2AHTTCYP1A2HTR2AHTR2B
SCHEMBL17274673 0.74 MRGPRX4 (0.46) MRGPRX4HTR2AHTR2CHTR2BTSHR
SCHEMBL5644761 0.74 MRGPRX4 (0.46) MRGPRX4CYP1A2CYP2C19TDP1CFD
SCHEMBL28500626 0.73 MRGPRX4 (0.42) MRGPRX4CYP1A2GCKTSHR
SCHEMBL31426438 0.73 MRGPRX4 (0.67) MRGPRX4MEN1KMT2ATDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102731382-B 6-(polysubstituted aryl)-4-aminopyridine manthanoate and the purposes as weedicide thereof THE DOW AGROSCIENCES, LLC. (US) 2015-09-02 CN disclosed