Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 10/20 | 0.52 |
| ▸ | HTR1D | P28221 | 9/20 | 0.52 |
| ▸ | HTR1A | P08908 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28034417 | 0.88 | HTT (0.56) | HTTHTR1BHTR1DHTR1AMAPT | |
| SCHEMBL23629467 | 0.82 | SLC22A6 (0.60) | SLC22A6HTR1DHTR1AMAPTTDP1 | |
| SCHEMBL27898848 | 0.80 | HTR1D (0.60) | HTTSLC22A6HTR1BHTR1DHTR1A | |
| SCHEMBL23269931 | 0.77 | HTR1B (0.71) | HTTHTR1BHTR1DHTR1AMAPT | |
| SCHEMBL28758142 | 0.77 | HTR1B (0.49) | HTTHTR1BHTR1DHTR1AMAPT | |
| SCHEMBL12721122 | 0.76 | KDM4E (0.71) | HTTHTR1BHTR1DHTR1AMAPT | |
| SCHEMBL12721389 | 0.76 | MAPT (0.71) | HTTHTR1BHTR1DHTR1AMAPT | |
| SCHEMBL6558468 | 0.76 | KDM4E (0.45) | HTTKDM4ETP53 | |
| SCHEMBL9117858 | 0.76 | SLC22A6 (0.64) | HTTSLC22A6HTR1DKDM4ETP53 | |
| SCHEMBL12247689 | 0.76 | HTR1B (0.60) | HTTHTR1BHTR1DHTR1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104936591-B | Hematopoietin expression facilitator | 国立大学法人东北大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-104936591-A | Erythropoietin expression promoter | UNIV TOHOKU NAT UNIV CORP | 2015-09-23 | — | — | CN | disclosed |