Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28034943 | 0.86 | NR4A2 (0.55) | NR4A2LMNABRCA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28034314 | 0.85 | CNR2 (0.57) | ALDH1A1KDM4E | |
| SCHEMBL8121101 | 0.84 | CNR2 (0.62) | — | |
| SCHEMBL28092635 | 0.84 | IDO1 (0.52) | LMNABRCA1ALDH1A1SMN1; SMN2SLC22A6 | |
| SCHEMBL9056926 | 0.84 | LMNA (0.58) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28034310 | 0.83 | CNR2 (0.60) | — | |
| SCHEMBL28034290 | 0.83 | CNR2 (0.60) | — | |
| SCHEMBL10698031 | 0.79 | NR4A2 (0.53) | NR4A2LMNAALDH1A1SMN1; SMN2SLC22A6 | |
| SCHEMBL12614628 | 0.78 | NR4A2 (0.55) | NR4A2LMNABRCA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10863325 | 0.78 | NR4A2 (0.52) | NR4A2LMNABRCA1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526903-A | Bisindole maleimide derivative and its preparation method and application | OCEAN UNIV CHINA | 2019-12-03 | — | — | CN | disclosed |
| CN-110218206-A | Bisindole maleimide derivative and its preparation method and application | 中国海洋大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-106083830-B | Bisindolylmaleimide derivative and preparation method and application thereof | 中国海洋大学 | 2019-07-12 | — | — | CN | disclosed |
| CN-106146475-B | Bisindolylmaleimide derivative and preparation method and application thereof | 中国海洋大学 | 2019-05-17 | — | — | CN | disclosed |
| CN-106146475-A | Bisindolylmaleimide derivative and preparation method and application thereof | 中国海洋大学 | 2016-11-23 | — | — | CN | disclosed |
| CN-106083830-A | Bisindolylmaleimide derivative and preparation method and application thereof | 中国海洋大学 | 2016-11-09 | — | — | CN | disclosed |
| CN-104936591-A | Erythropoietin expression promoter | UNIV TOHOKU NAT UNIV CORP | 2015-09-23 | — | — | CN | disclosed |