Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455781 | 0.86 | ALDH1A1 (0.50) | ALDH1A1CYP2D6MAPTGAAKDM4E | |
| SCHEMBL9138871 | 0.86 | ALDH1A1 (0.50) | ALDH1A1CYP2D6MAPTGAAKDM4E | |
| SCHEMBL27745058 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CYP2D6MAPTGAAKDM4E | |
| SCHEMBL18458413 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL16957062 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP2D6MAPTGAAKDM4E | |
| SCHEMBL25329112 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CYP2D6MAPTGAAKDM4E | |
| SCHEMBL4434685 | 0.81 | ALDH1A1 (0.53) | ALDH1A1EPAS1MAPTGAAKDM4E | |
| SCHEMBL15762737 | 0.81 | EPAS1 (0.48) | ALDH1A1CYP2D6EPAS1APPMAPT | |
| SCHEMBL6741460 | 0.80 | ALDH1A1 (0.45) | ALDH1A1CYP2D6MAPTGAAKDM4E | |
| SCHEMBL6746791 | 0.80 | ALDH1A1 (0.45) | ALDH1A1CYP2D6MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119859155-A | Tri-fused ring derivative inhibitor, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-105085433-B | Substituted amide phenol compound and preparation method thereof, pharmaceutical composition and purposes | 中国科学院上海药物研究所 | 2019-06-25 | — | — | CN | disclosed |
| CN-105085433-A | Substituted-amide phenolic compound, preparation method, pharmaceutical composition and application thereof | SHANGHAI INST MATERIA MEDICA | 2015-11-25 | — | — | CN | disclosed |