Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 7/20 | 0.46 |
| ▸ | PDE4A | P27815 | 4/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28035087 | 1.00 | PDE5A (0.46) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8448199 | 0.91 | SMPD1 (0.39) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1392449 | 0.91 | SMPD1 (0.39) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30311148 | 0.91 | SMPD1 (0.39) | PDE5APDE4APDE4BPDE4CPDE4D | |
| Zinc Ion SCHEMBL1392695 | 0.89 | SMPD1 (0.38) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1619886 | 0.89 | SMPD1 (0.38) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15859541 | 0.89 | SMPD1 (0.38) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1393356 | 0.89 | SMPD1 (0.38) | PDE5APDE4APDE4BPDE4CPDE4D | |
| Water SCHEMBL1393371 | 0.88 | SMPD1 (0.40) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5707000 | 0.84 | PDE5A (0.45) | PDE5APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102863448-B | A kind of Effects of Soluble Phthalocyanines, its preparation method and a kind of OTFT | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2015-10-07 | — | — | CN | disclosed |