Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.44 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3550114 | 0.88 | DNM1 (0.59) | DNM1CYP2C9CYP2C19ACKR3KDM4A | |
| Hydrochloric Acid SCHEMBL55352 | 0.86 | DNM1 (0.58) | DNM1CYP2C9CYP2C19ACKR3KDM4A | |
| SCHEMBL9506009 | 0.85 | DNM1 (0.70) | DNM1KDM4AHIF1ATET2DOHH | |
| SCHEMBL9504615 | 0.84 | DNM1 (0.73) | DNM1KDM4AHIF1ATET2DOHH | |
| SCHEMBL9507687 | 0.84 | DNM1 (0.63) | DNM1KDM4AHIF1ATET2DOHH | |
| SCHEMBL15858234 | 0.84 | DNM1 (0.63) | DNM1KDM4AHIF1ATET2DOHH | |
| SCHEMBL12254769 | 0.82 | DNM1 (0.68) | DNM1ACKR3TP53MAPTCA1 | |
| SCHEMBL10086103 | 0.82 | DNM1 (0.86) | DNM1ACKR3TP53MAPT | |
| Hydrochloric Acid SCHEMBL1930572 | 0.82 | DNM1 (0.71) | DNM1KDM4AHIF1ATET2DOHH | |
| Hydrochloric Acid SCHEMBL1931188 | 0.82 | DNM1 (0.71) | DNM1KDM4AHIF1ATET2DOHH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263906-B | The inhibitor of histone demethylase | 吉利德科学公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-105263906-A | Inhibitors of histone demethylases | EPITHERAPEUTICS APS | 2016-01-20 | — | — | CN | disclosed |
| CN-104981458-A | Inhibitors of histone demethylases | EPITHERAPEUTICS APS | 2015-10-14 | — | — | CN | disclosed |