Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | CASP1 | P29466 | 5/20 | 0.55 |
| ▸ | CASP7 | P55210 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3323519 | 0.91 | KDM4E (0.57) | KDM4EALDH1A1CASP1CASP7HPGD | |
| SCHEMBL12932104 | 0.91 | KDM4E (0.58) | KDM4EALDH1A1CASP1CASP7HPGD | |
| SCHEMBL5328210 | 0.90 | ALDH1A1 (0.62) | KDM4EALDH1A1CASP1CASP7HPGD | |
| SCHEMBL5331530 | 0.88 | ALDH1A1 (0.48) | KDM4EALDH1A1CASP1CASP7HPGD | |
| SCHEMBL3324542 | 0.87 | TP53 (0.51) | KDM4EALDH1A1CASP1CASP7HPGD | |
| SCHEMBL30195593 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1CASP1CASP7HPGD | |
| SCHEMBL29392482 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1CASP1CASP7HPGD | |
| SCHEMBL644336 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1CASP1CASP7HPGD | |
| SCHEMBL12932119 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1CASP1CASP7HPGD | |
| SCHEMBL12932106 | 0.86 | ALDH1A1 (0.67) | KDM4EALDH1A1CASP1CASP7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008518-A | Culturing of human embryonic stem cells at the air-liquid interface for differentiation into pancreatic endocrine cells | JANSSEN BIOTECH INC | 2015-10-28 | — | — | CN | disclosed |