Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | CDC42 | P60953 | 1/20 | 0.38 |
| ▸ | RAC1 | P63000 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29290383 | 0.74 | RARA (0.40) | ACMSDRARARARBRARGAKR1C3 | |
| SCHEMBL875225 | 0.73 | — | — | |
| SCHEMBL2222755 | 0.72 | PPARG (0.41) | FFAR1PTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL2221493 | 0.72 | NCEH1 (0.48) | PTGS2AKR1C3AKR1C2PTGS1CDC42 | |
| SCHEMBL28146822 | 0.71 | — | — | |
| SCHEMBL28046112 | 0.71 | — | — | |
| SCHEMBL11668578 | 0.71 | — | — | |
| SCHEMBL11773199 | 0.71 | — | — | |
| SCHEMBL27996074 | 0.71 | — | — | |
| SCHEMBL11512060 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111054-A | Curcumin analogue with enlarged conjugated system and preparation method and application thereof | UNIV LIAOCHENG | 2015-12-02 | — | — | CN | claimed |
| CN-105111054-A | Curcumin analogue with enlarged conjugated system and preparation method and application thereof | UNIV LIAOCHENG | 2015-12-02 | — | — | CN | disclosed |