Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784792 | 0.81 | POLB (0.55) | POLBF2RL1NPC1RAB9APKM | |
| SCHEMBL474014 | 0.81 | CYP2D6 (0.51) | POLBIDO1KDM4ESLC6A2SLC6A3 | |
| SCHEMBL27974256 | 0.80 | POLB (0.43) | POLBTDP1IDO1MTNR1ANPC1 | |
| SCHEMBL473994 | 0.79 | SLC6A4 (0.45) | POLBIDO1KDM4ESLC6A2SLC6A3 | |
| SCHEMBL9921242 | 0.79 | SLC6A4 (0.45) | POLBMAPTSLC6A2SLC6A3GPR139 | |
| SCHEMBL31204494 | 0.79 | TDP1 (0.44) | POLBTDP1IDO1KDM4ELMNA | |
| SCHEMBL8340513 | 0.78 | SLC6A4 (0.47) | POLBTDP1IDO1KDM4ESLC6A2 | |
| SCHEMBL15876278 | 0.78 | POLB (0.43) | POLBTDP1IDO1MTNR1AGPR139 | |
| SCHEMBL17767019 | 0.78 | CYP3A4 (0.47) | POLBTDP1IDO1NPC1RAB9A | |
| SCHEMBL473881 | 0.78 | HSD17B10 (0.63) | POLBTDP1KDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102548976-B | (thio) morpholine derivatives as S1P modulators | ABBVIE BAHAMAS LTD. (BS) | 2015-09-09 | — | — | CN | disclosed |