Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14378134 | 1.00 | ALDH1A1 (0.47) | ALDH1A1POLBCA12CA7CA9 | |
| SCHEMBL2421309 | 0.81 | MAPT (0.54) | ALDH1A1CA12CA9SMN1; SMN2TDP1 | |
| SCHEMBL27735039 | 0.81 | MAPT (0.54) | ALDH1A1CA12CA9SMN1; SMN2TDP1 | |
| SCHEMBL1938001 | 0.79 | ALDH1A1 (0.51) | ALDH1A1POLBCA12CA7CA9 | |
| SCHEMBL7955002 | 0.78 | CA12 (0.57) | ALDH1A1POLBCA12CA7CA9 | |
| SCHEMBL3885828 | 0.76 | CNR2 (0.57) | ALDH1A1POLBCA12CA7CA9 | |
| SCHEMBL10080089 | 0.76 | CNR2 (0.57) | ALDH1A1POLBCA12CA7CA9 | |
| SCHEMBL182775 | 0.76 | CNR2 (0.57) | ALDH1A1POLBCA12CA7CA9 | |
| SCHEMBL31048573 | 0.75 | MAPT (0.44) | LMNAMAPT | |
| SCHEMBL9184442 | 0.75 | ALDH1A1 (0.51) | ALDH1A1POLBCA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104003913-B | The preparation method of E-3,4-dihydroxyphenyl vinylic sulfonamides and sulfonates compounds and the application as neuroprotective thereof | PEKING UNIVERSITY (CN) | 2015-10-07 | — | — | CN | disclosed |