Pipemidic Acid

Pipemidic Acid

SCHEMBL28034962

CCn1cc(C(=O)O)c(=O)c2cnc(N3CCNCC3)nc21.[CaH2]

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.80
CASP1 P29466 1/20 0.80
KDM4E B2RXH2 6/20 0.64
CYP2C9 P11712 2/20 0.64
ATP6V1B2 P21281 1/20 0.64
TBXA2R P21731 1/20 0.64
EDNRA P25101 1/20 0.64
TARBP2 Q15633 1/20 0.64
MAPK1 P28482 3/20 0.61
ENPP2 Q13822 10/20 0.61
MEN1 O00255 1/20 0.61
ALDH1A1 P00352 1/20 0.61
HPGD P15428 1/20 0.61
KMT2A Q03164 1/20 0.61
HSD17B10 Q99714 1/20 0.61
NPSR1 Q6W5P4 1/20 0.59
TDP1 Q9NUW8 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pipemidic Acid SCHEMBL27316221 0.99 LMNA (0.82) LMNACASP1KDM4ECYP2C9ATP6V1B2
Pipemidic Acid SCHEMBL135557 0.99 LMNA (0.82) LMNACASP1KDM4ECYP2C9ATP6V1B2
Pipemidic Acid SCHEMBL29351712 0.99 LMNA (0.82) LMNACASP1KDM4ECYP2C9ATP6V1B2
Pipemidic Acid SCHEMBL11872870 0.98 LMNA (0.80) LMNACASP1KDM4ECYP2C9ATP6V1B2
Pipemidic Acid SCHEMBL9935838 0.98 LMNA (0.80) LMNACASP1KDM4ECYP2C9ATP6V1B2
Pipemidic Acid SCHEMBL675597 0.98 LMNA (0.80) LMNACASP1KDM4ECYP2C9ATP6V1B2
Pipemidic Acid SCHEMBL28034340 0.98 LMNA (0.80) LMNACASP1KDM4ECYP2C9ATP6V1B2
Pipemidic Acid SCHEMBL9073067 0.98 LMNA (0.80) LMNACASP1KDM4ECYP2C9ATP6V1B2
Pipemidic Acid SCHEMBL28757085 0.98 LMNA (0.80) LMNACASP1KDM4ECYP2C9ATP6V1B2
Pipemidic Acid SCHEMBL11870978 0.97 LMNA (0.78) LMNACASP1KDM4ECYP2C9ATP6V1B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105315574-B A kind of PVC calcium zinc heat stabilizers and its application 浙江工业大学 2018-10-23 CN claimed
CN-105315574-A Calcium and zinc heat stabilizer for PVC and application of calcium and zinc heat stabilizer UNIV ZHEJIANG TECHNOLOGY 2016-02-10 CN claimed
CN-105315574-B A kind of PVC calcium zinc heat stabilizers and its application 浙江工业大学 2018-10-23 CN disclosed
CN-105315574-A Calcium and zinc heat stabilizer for PVC and application of calcium and zinc heat stabilizer UNIV ZHEJIANG TECHNOLOGY 2016-02-10 CN disclosed