SCHEMBL28035137

SCHEMBL28035137

O=C(Cl)OC(=O)c1cccc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.55
NR4A2 P43354 1/20 0.55
NR4A3 Q92570 1/20 0.55
KMT2A Q03164 4/20 0.54
POLB P06746 1/20 0.54
GAA P10253 1/20 0.54
MMP3 P08254 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
CDC25B P30305 2/20 0.49
PTPN1 P18031 1/20 0.49
PLK1 P53350 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.47
PTK2B Q14289 1/20 0.47
HPGD P15428 5/20 0.47
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 5/20 0.46
MEN1 O00255 3/20 0.46
MAPT P10636 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HSP90AA1 P07900 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL137605 0.88 NR4A1 (0.63) NR4A1NR4A2NR4A3KMT2APOLB
SCHEMBL29459734 0.88 NR4A1 (0.63) NR4A1NR4A2NR4A3KMT2APOLB
SCHEMBL14672373 0.86 NR4A1 (0.61) NR4A1NR4A2NR4A3KMT2APOLB
Potassium SCHEMBL6929965 0.86 NR4A1 (0.61) NR4A1NR4A2NR4A3KMT2APOLB
SCHEMBL11422834 0.86 NR4A1 (0.61) NR4A1NR4A2NR4A3KMT2APOLB
SCHEMBL29262289 0.86 NR4A1 (0.61) NR4A1NR4A2NR4A3KMT2APOLB
Benzene SCHEMBL28284945 0.86 NR4A1 (0.67) NR4A1NR4A2NR4A3KMT2APOLB
Ethylene SCHEMBL10012407 0.85 NR4A1 (0.59) NR4A1NR4A2NR4A3KMT2APOLB
Hydrazine SCHEMBL28964205 0.85 NR4A1 (0.59) NR4A1NR4A2NR4A3KMT2APOLB
SCHEMBL27427211 0.83 NR4A1 (0.62) NR4A1NR4A2NR4A3KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105899284-A high-swelling composite polyamide membrane 陶氏环球技术有限责任公司 2016-08-24 CN disclosed
CN-105873665-A Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2016-08-17 CN disclosed
CN-105377406-A Composite polyamide membrane comprising a trihydrocarbon phosphate DOW GLOBAL TECHNOLOGIES INC 2016-03-02 CN disclosed
CN-104918687-A Composite polyamide membranes made via interfacial polymerization using blends of non-polar solvents DOW GLOBAL TECHNOLOGIES LLC 2015-09-16 CN disclosed