Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TOP1 | P11387 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL9568837 | 0.85 | ALDH1A1 (0.54) | MAPTABCC4ALDH1A1ALOX15TOP1 | |
| Phthalic Acid SCHEMBL21332399 | 0.85 | ALDH1A1 (0.64) | MAPTALDH1A1ALOX15HPGDHSD17B10 | |
| Phthalic Acid SCHEMBL23929048 | 0.85 | ALDH1A1 (0.64) | MAPTALDH1A1ALOX15HPGDHSD17B10 | |
| Undecylenic Acid SCHEMBL4884120 | 0.84 | MAPT (0.59) | MAPTABCC4ALDH1A1HPGDHDAC3 | |
| Phthalic Acid SCHEMBL10715717 | 0.84 | ALDH1A1 (0.52) | MAPTABCC4ALDH1A1ALOX15TOP1 | |
| Phthalic Acid SCHEMBL30480760 | 0.82 | ALDH1A1 (0.67) | MAPTALDH1A1ALOX15HPGDHSD17B10 | |
| Phthalic Acid SCHEMBL1906918 | 0.82 | ALDH1A1 (0.67) | MAPTALDH1A1ALOX15HPGDHSD17B10 | |
| Diphenylmethane SCHEMBL10648710 | 0.82 | TOP1 (0.56) | MAPTABCC4TOP1HDAC3HDAC4 | |
| Phthalic Acid SCHEMBL10624073 | 0.82 | ALDH1A1 (0.50) | MAPTABCC4ALDH1A1ALOX15TOP1 | |
| Phthalic Acid SCHEMBL10585910 | 0.82 | ALDH1A1 (0.50) | ALDH1A1ALOX15HPGDKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103370334-B | Modified human tumor necrosis factor receptor-I polypeptide or fragment thereof and preparation method thereof | 韩诺生物制药株式会社 | 2016-06-22 | — | — | CN | disclosed |
| CN-102574907-B | The human tumor necrosis factor receptor I polypeptide of modifying or its fragment and prepare their method | HANALL BIOPHARMA CO.,LTD. (KR) | 2015-10-21 | — | — | CN | disclosed |