(2E)-Hexenoic Acid

(2E)-Hexenoic Acid

SCHEMBL28035225

CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)O.CCCC=CC(=O)OC.CCCC=CC(=O)OC

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.58
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48
ALDH1A1 P00352 2/20 0.43
ALOX15 P16050 1/20 0.43
RECQL P46063 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TAS1R3 Q7RTX0 1/20 0.43
TAS1R1 Q7RTX1 1/20 0.43
MAPT P10636 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
KDM4E B2RXH2 1/20 0.42
PTPN1 P18031 1/20 0.39
GABRR1 P24046 2/20 0.38
GABRR2 P28476 2/20 0.38
BLM P54132 2/20 0.38
GABRR3 A8MPY1 1/20 0.38
LMNA P02545 1/20 0.38
TSHR P16473 1/20 0.38
APEX1 P27695 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(2E)-Hexenoic Acid SCHEMBL2191923 1.00 HCAR2 (0.58) HCAR2KEAP1NFE2L2ALDH1A1ALOX15
SCHEMBL873968 0.94
SCHEMBL873967 0.94
SCHEMBL18120374 0.94
SCHEMBL17629430 0.87 PTPN1 (0.55) HCAR2ALOX15RECQLHSD17B10MAPT
(2E)-Hexenoic Acid SCHEMBL28221343 0.87 TAS1R3 (0.46) HCAR2TAS1R3TAS1R1TDP1PTPN1
SCHEMBL4584292 0.86 MAPT (0.50) HCAR2KEAP1NFE2L2ALDH1A1TAS1R3
SCHEMBL4936586 0.86 MAPT (0.50) HCAR2KEAP1NFE2L2ALDH1A1TAS1R3
SCHEMBL4582554 0.86 HCAR2 (0.46) HCAR2KEAP1NFE2L2ALOX15RECQL
SCHEMBL4939935 0.86 HCAR2 (0.46) HCAR2KEAP1NFE2L2ALOX15RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105688434-B It is a kind of can be used for separation physical property be similar or the tower of heat-sensitive substance in pump suction type high vacuum rectification method and apparatus 天津大学 2018-02-09 CN disclosed
CN-105688434-A In-tower pumping type high vacuum rectification method for separating substances with similar physical properties or thermo-sensitive substances and device 天津大学 2016-06-22 CN disclosed
CN-105001997-A Method and device for separating and extracting high value-added fatty acid methyl ester in animal and vegetable oil through electromagnetic wave vacuum distillation UNIV TIANJIN 2015-10-28 CN disclosed