Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27632090 | 0.82 | CA1 (0.39) | NR4A2NPC1RAB9ASMN1; SMN2SLC6A3 | |
| SCHEMBL27519436 | 0.81 | NR4A2 (0.39) | NR4A2NR4A1NR4A3MAOBSRD5A2 | |
| SCHEMBL27620271 | 0.78 | RXRA (0.32) | — | |
| SCHEMBL27937750 | 0.78 | TAAR1 (0.33) | SMN1; SMN2BACE1 | |
| SCHEMBL27997806 | 0.77 | MRGPRX4 (0.40) | FFAR1AMPD2 | |
| SCHEMBL27413672 | 0.76 | RXFP1 (0.35) | MCL1PTPN1 | |
| SCHEMBL28093247 | 0.76 | SRD5A1 (0.36) | SRD5A2ALOX5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27371651 | 0.76 | BCL2L1 (0.38) | PTGS1CYP2C19PTGS2 | |
| SCHEMBL28141341 | 0.75 | TSHR (0.39) | NR4A2NR4A1NR4A3NPC1RAB9A | |
| SCHEMBL27988444 | 0.74 | RXRA (0.36) | AMPD2LMNAHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981472-A | Heteroaromatic compounds and their use as dopamine d1 ligands | PFIZER | 2015-10-14 | — | — | CN | disclosed |