Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.64 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.61 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 3/20 | 0.45 |
| ▸ | FNTB | P49356 | 3/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24465876 | 0.81 | MAPT (0.51) | IDO1BRD9HPGDSSRCDYRK1A | |
| SCHEMBL1502348 | 0.81 | BRD9 (0.52) | IDO1BRD9SRCEGLN2DYRK1A | |
| SCHEMBL17308284 | 0.79 | IDO1 (0.68) | IDO1BRD9HPGDSDYRK1ANPY5R | |
| SCHEMBL21128683 | 0.79 | IDO1 (0.68) | IDO1BRD9HPGDSDYRK1AGSK3B | |
| SCHEMBL7128025 | 0.78 | IDO1 (0.66) | IDO1BRD9HPGDSBRD4DYRK1A | |
| SCHEMBL1501843 | 0.78 | IDO1 (0.66) | IDO1HPGDSDYRK1AGSK3BCYP3A4 | |
| SCHEMBL30473398 | 0.78 | IDO1 (0.66) | IDO1BRD9HPGDSBRD4DYRK1A | |
| SCHEMBL23539669 | 0.78 | IDO1 (1.00) | IDO1HPGDSEGLN2DYRK1AGSK3B | |
| SCHEMBL23119634 | 0.78 | IDO1 (0.66) | IDO1BRD9HPGDSTP53GAA | |
| SCHEMBL30042691 | 0.78 | IDO1 (1.00) | IDO1HPGDSEGLN2DYRK1AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109126875-B | Carbon 60-bidentate nitrogen heterocyclic carbene palladium (0) compound and preparation method and application thereof | 洛阳师范学院 | 2021-03-16 | — | — | CN | disclosed |
| CN-104981472-A | Heteroaromatic compounds and their use as dopamine d1 ligands | PFIZER | 2015-10-14 | — | — | CN | disclosed |