Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | LDLR | P01130 | 1/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 3/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | SELE | P16581 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28035340 | 0.81 | IDO1 (0.64) | MAPTCYP11B1CYP11B2GSK3BDYRK1A | |
| SCHEMBL19981228 | 0.81 | ATP1A1 (0.45) | GSK3BDYRK1AIDO1HPGDSLDLR | |
| SCHEMBL1502339 | 0.79 | IDO1 (0.51) | CYP11B1CYP11B2GSK3BDYRK1AIDO1 | |
| SCHEMBL10985757 | 0.77 | CYP11B1 (0.51) | MAPTCYP11B1CYP11B2QPCTQPCTL | |
| SCHEMBL5779888 | 0.77 | IDO1 (0.50) | GSK3BDYRK1AIDO1HPGDSTDP1 | |
| Ammonia Solution, Strong SCHEMBL28862527 | 0.77 | IDO1 (0.50) | CYP11B1CYP11B2GSK3BDYRK1AIDO1 | |
| SCHEMBL15875301 | 0.77 | IDO1 (0.64) | CYP11B1CYP11B2GSK3BDYRK1AIDO1 | |
| SCHEMBL24185698 | 0.77 | IDO1 (0.50) | GSK3BDYRK1AIDO1HPGDSCHEK1 | |
| SCHEMBL22874232 | 0.77 | IDO1 (0.59) | GSK3BDYRK1AIDO1HPGDS | |
| SCHEMBL10985317 | 0.77 | IDO1 (0.53) | GSK3BDYRK1AIDO1HPGDSLDLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006013-A1 | NOVEL SMALL MOLECULE COMPOUND INHIBITING SIGNAL TRANSMISSION PATH OF TLR7 AND TLR9 AND USE THEREOF | Ajou University Industry-Academic Cooperation Foundation (KR) | 2022-06-01 | — | — | EP | disclosed |