Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 7/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187076 | 0.82 | KDM1A (0.51) | SMN1; SMN2NPSR1KDM1AHTR2AHTR2C | |
| SCHEMBL8334238 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2NPSR1KDM1AMAOBHRH3 | |
| SCHEMBL25695438 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2NPSR1KDM1AMAOBHRH3 | |
| Hydrochloric Acid SCHEMBL28626845 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2NPSR1KDM1AMAOBHRH3 | |
| SCHEMBL8104288 | 0.78 | HTR2C (0.52) | GAAKDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL8104287 | 0.78 | HTR2C (0.52) | GAAKDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL15776493 | 0.78 | KDM1A (0.58) | KDM1AHTR2AHTR2CHTR2BMAOB | |
| SCHEMBL21048167 | 0.77 | KDM1A (0.57) | SMN1; SMN2NPSR1KDM1AHTR2AHTR2C | |
| SCHEMBL20453815 | 0.77 | IDO1 (0.39) | GAASMN1; SMN2NPSR1KDM1AMAOB | |
| SCHEMBL26791810 | 0.75 | DPP4 (0.48) | SMN1; SMN2NPSR1KDM1AMAOBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105120869-A | Treatment of ocular disorders | KADMON CORP LLC | 2015-12-02 | — | — | CN | disclosed |
| CN-105101996-A | Treatment of ocular disorders | KADMON CORP LLC | 2015-11-25 | — | — | CN | disclosed |