Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17908009 | 0.83 | SLC22A6 (0.46) | TDP1SMN1; SMN2SLC22A6GPR84MAPT | |
| SCHEMBL3837519 | 0.82 | TDP1 (0.42) | TDP1GPR84FFAR3TP53 | |
| SCHEMBL2956099 | 0.82 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6MAPTGABRR1 | |
| SCHEMBL687714 | 0.82 | TDP1 (0.42) | TDP1GPR84FFAR3TP53 | |
| SCHEMBL10474787 | 0.82 | TDP1 (0.54) | TDP1SMN1; SMN2SLC22A6GPR84LMNA | |
| SCHEMBL13539674 | 0.81 | TDP1 (0.48) | TDP1SMN1; SMN2SLC22A6GPR84MAPT | |
| SCHEMBL1999411 | 0.81 | TDP1 (0.52) | TDP1SMN1; SMN2SLC22A6GPR84MAPT | |
| SCHEMBL9782163 | 0.81 | TDP1 (0.52) | TDP1SMN1; SMN2SLC22A6GPR84MAPT | |
| SCHEMBL10892131 | 0.81 | TDP1 (0.52) | TDP1SMN1; SMN2SLC22A6GPR84MAPT | |
| SCHEMBL3245749 | 0.80 | TDP1 (0.74) | TDP1SMN1; SMN2SLC22A6GPR84MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884050-A | pharmaceutical composition for treating HIV infection | OTKRYTOE AKTSIONERNOE OBSCHESTVO FARMASYNTEZ | 2015-09-02 | — | — | CN | disclosed |