Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ARG2 | P78540 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 1/20 | 0.37 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28327198 | 0.85 | MAOB (0.39) | MAOBALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL28771086 | 0.85 | ALDH1A1 (0.47) | ALDH1A1TRPV1MAPTMAPK1L3MBTL1 | |
| SCHEMBL27744106 | 0.84 | MAOB (0.45) | MAOBKMT2A | |
| SCHEMBL27758613 | 0.84 | MAOB (0.45) | MAOBKMT2A | |
| SCHEMBL10325277 | 0.83 | ALDH1A1 (0.56) | MAOBTOP1ALDH1A1TRPV1CA1 | |
| SCHEMBL10325275 | 0.83 | ALDH1A1 (0.56) | MAOBTOP1ALDH1A1TRPV1CA1 | |
| SCHEMBL14775503 | 0.80 | MAOB (0.58) | MAOBTOP1ALDH1A1CA1CA2 | |
| SCHEMBL14775505 | 0.80 | MAOB (0.58) | MAOBTOP1ALDH1A1CA1CA2 | |
| SCHEMBL27764982 | 0.80 | KMT2A (0.40) | ALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL15578517 | 0.79 | TOP1 (0.55) | MAOBTOP1ALDH1A1TRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103274957-B | The synthetic method of α, α-disubstituted amido acid derivative | EAST CHINA NORMAL UNIVERSITY (CN) | 2015-10-28 | — | — | CN | claimed |
| CN-103274957-B | The synthetic method of α, α-disubstituted amido acid derivative | EAST CHINA NORMAL UNIVERSITY (CN) | 2015-10-28 | — | — | CN | disclosed |