Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 7/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4159762 | 0.84 | PTGES2 (0.44) | PTGS2HTR6HTR2C | |
| SCHEMBL4279326 | 0.83 | PTGS2 (0.46) | PTGS2PTGDR2LMNAMYC | |
| SCHEMBL10408635 | 0.82 | PTGS2 (0.40) | PTGS2PTGDR2MYC | |
| SCHEMBL27952944 | 0.81 | PTGS2 (0.45) | PTGS2PTGDR2LMNAMYC | |
| Water SCHEMBL30194738 | 0.81 | PTGS2 (0.39) | PTGS2PTGDR2MYC | |
| SCHEMBL28062056 | 0.81 | TTR (0.41) | PTGS2PTGDR2 | |
| SCHEMBL23664866 | 0.80 | PTGS2 (0.44) | PTGS2HTR6HTR2CLMNA | |
| SCHEMBL8589905 | 0.79 | TTR (0.42) | PTGS2PTGDR2 | |
| SCHEMBL27828565 | 0.79 | PTGS2 (0.36) | PTGS2PTGDR2 | |
| SCHEMBL31240954 | 0.78 | HTR2C (0.52) | PTGS2HTR6HTR2CPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105012306-A | SAA derivative compounds in hypoxic state are capable of reducing eNOS and inhibiting oxidative stress induced diseases | JIANZHI BIOLOG TECHNOLOGY CO LTD | 2015-11-04 | — | — | CN | disclosed |