Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20997551 | 0.80 | TSHR (0.35) | — | |
| SCHEMBL19476970 | 0.78 | S1PR1 (0.41) | S1PR1S1PR3S1PR5S1PR4MAOB | |
| SCHEMBL19122392 | 0.77 | OPRM1 (0.48) | S1PR1S1PR3S1PR5S1PR4EBP | |
| SCHEMBL24316054 | 0.76 | S1PR4 (0.34) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL14131261 | 0.76 | S1PR1 (0.41) | S1PR1S1PR3S1PR5S1PR4EBP | |
| SCHEMBL27097523 | 0.74 | OPRM1 (0.43) | S1PR1S1PR3S1PR5S1PR4EBP | |
| SCHEMBL23466099 | 0.74 | SLC22A1 (0.34) | — | |
| SCHEMBL19808331 | 0.73 | CHRM5 (0.39) | SIGMAR1 | |
| SCHEMBL18506730 | 0.72 | S1PR1 (0.49) | S1PR1S1PR3S1PR5S1PR4MAOB | |
| SCHEMBL28239512 | 0.70 | S1PR1 (0.41) | S1PR1S1PR3S1PR5S1PR4EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008353-A | 2-acylaminothiazole derivative or salt thereof | ASTELLAS PHARMA INC | 2015-10-28 | — | — | CN | disclosed |