Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662971 | 0.86 | TDP1 (0.65) | TDP1LMNA | |
| SCHEMBL9844172 | 0.86 | TDP1 (0.64) | TDP1LMNAMAPK1ALDH1A1 | |
| SCHEMBL132946 | 0.84 | TDP1 (0.81) | TDP1LMNATSHRMAPK1CYP3A4 | |
| Benzene SCHEMBL28221398 | 0.84 | TDP1 (0.81) | TDP1LMNATSHRMAPK1CYP3A4 | |
| SCHEMBL28036335 | 0.83 | TDP1 (0.56) | TDP1LMNATSHRMAPK1CYP3A4 | |
| SCHEMBL246510 | 0.83 | TDP1 (0.79) | TDP1LMNATSHRMAPK1CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL11710929 | 0.83 | TDP1 (0.79) | TDP1LMNATSHRMAPK1CYP3A4 | |
| SCHEMBL1037965 | 0.83 | TDP1 (0.79) | TDP1LMNATSHRMAPK1CYP3A4 | |
| SCHEMBL20822083 | 0.83 | TDP1 (0.79) | TDP1LMNATSHRMAPK1CYP3A4 | |
| SCHEMBL10532726 | 0.83 | TDP1 (0.79) | TDP1LMNATSHRMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981452-A | Skin whitening agent containing novel cyclic compound | RNS CO LTD | 2015-10-14 | — | — | CN | disclosed |