Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662971 | 0.94 | TDP1 (0.65) | TDP1LMNAKMT2AMEN1SCN1A | |
| SCHEMBL26324134 | 0.88 | TDP1 (0.60) | TDP1LMNAKMT2AMEN1SCN1A | |
| SCHEMBL28035865 | 0.86 | TDP1 (0.58) | TDP1LMNAMAPK1ALDH1A1 | |
| SCHEMBL27898323 | 0.84 | TDP1 (0.58) | TDP1LMNAKMT2AMEN1SCN1A | |
| SCHEMBL19056808 | 0.83 | TDP1 (0.49) | TDP1LMNAMAPK1ALDH1A1 | |
| Benzoic Acid 2,3-Epoxypropyl Ester SCHEMBL133986 | 0.80 | NPC1 (0.56) | TDP1MAPK1HIF1A | |
| Benzoic Acid 2,3-Epoxypropyl Ester SCHEMBL5604855 | 0.80 | NPC1 (0.56) | TDP1MAPK1HIF1A | |
| Benzoic Acid 2,3-Epoxypropyl Ester SCHEMBL21245419 | 0.80 | NPC1 (0.56) | TDP1MAPK1HIF1A | |
| Benzoic Acid 2,3-Epoxypropyl Ester SCHEMBL14570069 | 0.80 | NPC1 (0.56) | TDP1MAPK1HIF1A | |
| SCHEMBL8408836 | 0.80 | TSHR (0.58) | TDP1LMNAKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |
| US-4259236-A | COLORFAST RED SHADES ON POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |