M-Xylene

M-Xylene

SCHEMBL28035950

CC(CC(C)c1ccccc1C(=O)O)c1ccccc1C(=O)O.Cc1cccc(C)c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.50
ALDH1A1 P00352 5/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
KCNK3 O14649 1/20 0.44
KCNK9 Q9NPC2 1/20 0.44
KDM4E B2RXH2 2/20 0.42
GAA P10253 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NOTUM Q6P988 1/20 0.40
ALOX15 P16050 1/20 0.39
MAPT P10636 2/20 0.39
MAPK1 P28482 1/20 0.39
GFER P55789 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MCL1 Q07820 1/20 0.39
MYC P01106 1/20 0.39
AKR1C3 P42330 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28035959 0.83 ALDH1A1 (0.44) ALDH1A1KMT2AKDM4EGAATDP1
Isopropylbenzene SCHEMBL28035524 0.81 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1KDM4EGAA
Chlorobenzene SCHEMBL28035530 0.81 NR4A1 (0.45) ALDH1A1KMT2AMEN1KDM4EGAA
SCHEMBL9791467 0.80 CSNK2A1 (0.47) POLBALDH1A1KMT2AMEN1KDM4E
SCHEMBL9791464 0.80 CSNK2A1 (0.47) POLBALDH1A1KMT2AMEN1KDM4E
SCHEMBL28619311 0.79 POLB (0.51) POLBALDH1A1KMT2AMEN1KCNK3
Isobutylbenzene SCHEMBL28035953 0.78 DHODH (0.45) POLBALDH1A1KMT2AGAATDP1
Tert-Butylbenzene SCHEMBL28278111 0.78 HCAR2 (0.42) ALDH1A1KMT2AGAATDP1NOTUM
SCHEMBL28035522 0.77 POLB (0.43) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL5230221 0.76 ACE2 (0.50) POLBALDH1A1KMT2AKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107868152-A A kind of catalytic component, catalyst and its application for olefinic polymerization 中国石油化工股份有限公司 2018-04-03 CN claimed
CN-107868153-A A kind of catalytic component, catalyst and its application for olefinic polymerization 中国石油化工股份有限公司 2018-04-03 CN claimed
CN-105085726-B A kind of catalytic component and catalyst for olefinic polymerization 中国石油化工股份有限公司 2017-11-07 CN claimed
CN-105085746-B Catalytic component and its catalyst for propylene polymerization 中国石油化工股份有限公司 2017-09-29 CN claimed
CN-105085746-A Catalyst component for propylene polymerization, and catalyst thereof CHINA PETROLEUM & CHEMICAL 2015-11-25 CN claimed
CN-105085726-A Catalyst component for olefin polymerization, and catalyst for olefin polymerization CHINA PETROLEUM & CHEMICAL 2015-11-25 CN claimed
CN-105085726-B A kind of catalytic component and catalyst for olefinic polymerization 中国石油化工股份有限公司 2017-11-07 CN disclosed
CN-105085746-B Catalytic component and its catalyst for propylene polymerization 中国石油化工股份有限公司 2017-09-29 CN disclosed
CN-105085746-A Catalyst component for propylene polymerization, and catalyst thereof CHINA PETROLEUM & CHEMICAL 2015-11-25 CN disclosed
CN-105085726-A Catalyst component for olefin polymerization, and catalyst for olefin polymerization CHINA PETROLEUM & CHEMICAL 2015-11-25 CN disclosed